hrp0097p2-30 | Diabetes and Insulin | ESPE2023

Long-term follow-up for the first neonatal diabetes mellitus (NDM) due to KCNJ11 gene mutation who were successfully transferred from insulin to oral sulfonylurea in the Arabian Gulf.

Almutair Angham , Al Oraini Sultan

Introduction: NDM is a rare disease diagnosed in the first 12 months of life. It is either transient or permanent. Early recognition of mutation in KCNJ11 and ABCC8, which account for approximately 40% of NDM, is essential to consider oral sulfonylurea for responsiveness mutations.Aim: To study the efficacy and safety of oral sulfonylurea in a long-term follow-up (15 years) for the first successful switch from insulin to...